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4 3 4 4 1 3
Question
4-3+4+4-1-3
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Answer to a math question 4-3+4+4-1-3
Gene
4.5
108
Answers
$12-3-1-3$
$12-7$
$5$
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Your boss asks you to plan the sample size for a randomized, double-blind, controlled trial in the clinical development of a cure for irritable bowl disease. Current standard treatment shall be compared with a new treatment in this trial. The S3-guideline of AWM demonstrated a mean change of the summary score of the validated health related quality of life questionnaire at 8 weeks of 16 with standard deviation 23 under standard treatment. You quote the drop-out rate of 11% from literature (previous phase of clinical development). Your research yielded a clinically important effect of 4 that has been found to be the Minimal Clinically Important Difference (MCID). In order to demonstrate superiority of the new treatment over standard of care, you assume that the change in of the summary score of the validated health related quality of life questionnaire follows a normal distribution, and that the standard deviation is the same for both treatments. How many patientes would one need to recruit for the trial to demonstrate the clinically interesting difference between treatments at significance level 5% with 95% power?
The following table shows the frequency of care for some animal species in a center specializing in veterinary dentistry. Species % Dog 52.8 Cat 19.2 Chinchilla 14.4 Marmoset 6.2 Consider that the center only serves 10 animals per week. For a given week, what is the probability that at least two are not dogs? ATTENTION: Provide the answer to exactly FOUR decimal places
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I have a complex function I would like to integrate over. I can use two approaches and they should give the same solution. If I want to find the contour integral β«πΎπ§Β―ππ§ for where πΎ is the circle |π§βπ|=3 oriented counterclockwise I get the following: β«2π0π+3πππ‘β―β―β―β―β―β―β―β―β―β―β―β―β―β―β―β―β―π(π+3πππ‘)=β«2π03π(βπ+3πβππ‘)πππ‘ππ‘=18ππ If I directly apply the Residue Theorem, I would get β«πΎπ§Β―ππ§=2ππRes(π,π§=0)=2ππ
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